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ALS results from progressive loss of nerve cells (motor neurons) that control muscles that involved in voluntary movements. It may start in the motor neurons that control the upper extremity or lower extremity muscles and eventually all muscles (Figure 7). Sometimes muscles of speaking and swallowing (bulbar muscles) may also be involved. The affected muscles show loss of bulk and may twitch. Sometimes muscles may be stiff or go into cramps. EMG studies are crucial in making diagnosis of ALS.  For More Information: ALS

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Amyotrophic Lateral Sclerosis 

(ALS, Lou Gehrig’s disease)